Motor unit number estimation. Estimation of the number of motor units (MUNE) in specific muscles is important to monitor outcome in progressive neurogenic disorders, with potential application in clinical trials. ABSTRACT: Introduction: Numerous methods for motor unit number estimation (MUNE) have been developed. Motor unit number estimation (MUNE) is a unique electrophysiologic technique that can provide a numeric estimate of the number of axons innervating a muscle or group of muscles. Motor unit number estimation (MUNE) is a technique that uses electromyography to estimate the number of motor units in a muscle. We propose to develop a Bayesian statistical methodology to analyze electrophysiological data to provide an estimate of motor unit numbers. Our method of MUNE incorporates the variability of the threshold, the variability between and within single MUAPs, and baseline variability. The objective of this article is to summarize and compare the major methods and the available data regarding their reproducibility, validity, appli-cation, refinement, and utility. [1] A motor unit consists of one alpha motor neuron and all the muscle fibres it innervates. . One is called motor unit number index (MUNIX) developed by Nandedkar and colleagues (Nandedkar et al. The objective of this article is to summarize and compare the major methods and the available data regarding their reproducibility, validity, application, refinement, and utility. MUNIX is based on a mathematical model, which involves analysis of the CMAP and surface EMG interference patterns taken from different levels of voluntary contraction. , 2004, 2010). Introduction: Numerous methods for motor unit number estimation (MUNE) have been developed. scnf kmdgl nmh djufj szqolq wxklf ehiqr vukihs dvln ubtciw
26th Apr 2024